What organ is affected by psoriasis?

Psoriasis is often seen as a skin condition characterised by red, scaly patches that can be itchy or painful. While the skin is the primary organ affected, understanding psoriasis means recognising that it’s more than skin deep. Psoriasis is an autoimmune condition where the immune system attacks healthy cells, particularly in the skin. However, its systemic nature means that other organs can be influenced by this immune response.

The Skin and Psoriasis

The most evident manifestation of psoriasis is on the skin. When the immune system erroneously targets skin cells, it accelerates the skin cell production process. This rapid production causes cells to accumulate on the surface, resulting in the formation of psoriatic patches.

Characteristics of Psoriatic Skin Lesions:

  • Plaques: These raised, red patches covered with silvery scales are the most common form of psoriatic lesions.
  • Itchiness and Pain: These patches can be itchy and painful. Some might even crack and bleed.
  • Distribution: Commonly affected areas include the elbows, knees, scalp, and lower back. However, any skin surface can be involved.

“Psoriasis is more than a skin condition; it’s an indicator of an overactive immune response that can influence multiple organs.”

Does psoriatic arthritis cause bowel problems?

Psoriasis’s systemic nature can lead to a related condition known as psoriatic arthritis (PsA), impacting joints. Beyond the joints, there’s a notable link between PsA and bowel problems, illustrating the condition’s far-reaching implications.

Psoriatic Arthritis and the Gut:

  • Inflammation: PsA can cause inflammation in the gut, leading to symptoms like diarrhoea and stomach cramps.
  • Increased Risk of Crohn’s Disease: Research in the UK has noted a higher prevalence of Crohn’s disease, an inflammatory bowel disease, among PsA patients.
  • Gut Flora: Some studies suggest that an imbalance in gut bacteria may play a role in autoimmune conditions, potentially linking gut health with psoriatic conditions.

Other Organs and Systems Affected by Psoriasis

The systemic inflammatory nature of psoriasis means other organs and systems can be impacted:

Cardiovascular System:

  • There’s an increased risk of cardiovascular disease among those with psoriasis. The persistent inflammation can lead to issues like atherosclerosis.


  • Beyond skin symptoms, up to 30% of individuals with psoriasis develop psoriatic arthritis, leading to painful and swollen joints.

Mental Health:

  • The psychological burden of living with a chronic condition, particularly one as visible as psoriasis, can lead to mental health challenges. Depression and anxiety rates are higher among psoriasis patients.



  • Chronic inflammation can increase the risk of liver conditions. Additionally, certain treatments for psoriasis might have an impact on liver function.


Psoriasis, often viewed as a skin disorder, has implications that ripple throughout the body. From the cardiovascular system to mental health, its reach extends far beyond skin lesions. For those living with psoriasis, understanding the condition’s systemic nature is essential for comprehensive management. Regular medical check-ups and a multidisciplinary approach to care can help address the myriad challenges posed by psoriasis. Awareness and early intervention remain the cornerstones of managing this complex autoimmune condition.

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